Two recent lessons I have been involved in are using Google Earth with 2nd Graders and having 5th graders create audio books for Pre-K students.
Google Earth Lesson (2nd Grade):
Students start Google Earth and each person is allowed 5 minutes to explore the program. Click here, click there, spin the Earth this way and that. I find I have way less interruptions if you just give kids time to explore the program “their way”. Giving just 5 minutes gets all those “what’s this do?” out of the way.
After both kids have had a turn at exploring the program, they come up to the front of the room and we talk about what they learned or found cool.